Aminoacyl-tRNA hydrolase

Template:Infobox enzyme The enzyme aminoacyl-tRNA hydrolase (EC 3.1.1.29) catalyzes the reaction

N-substituted aminoacyl-tRNA + H₂O $\rightleftharpoons$ N-substituted amino acid + tRNA

This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name is aminoacyl-tRNA aminoacylhydrolase. Other names in common use include aminoacyl-transfer ribonucleate hydrolase, N-substituted aminoacyl transfer RNA hydrolase, and peptidyl-tRNA hydrolase.

Structural studies

As of late 2007, 9 structures have been solved for this class of enzymes, with PDB accession codes Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, and Template:PDB link.

References

• Template:Cite journal

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