Alpha-1,6-mannosyl-glycoprotein 4-b-N-acetylglucosaminyltransferase
Template:Short description Template:Infobox enzyme Alpha-1,6-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase (Template:EC number, N-acetylglucosaminyltransferase VI, N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase VI, uridine diphosphoacetylglucosamine-glycopeptide beta-1->4-acetylglucosaminyltransferase VI, mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, GnTVI) is an enzyme with systematic name UDP-N-acetyl-D-glucosamine:2,6-bis(N-acetyl-beta-D-glucosaminyl)-alpha-D-mannosyl-glycoprotein 4-beta-N-acetyl-D-glucosaminyltransferase.[1][2] This enzyme catalyses the following chemical reaction
- UDP-N-acetyl-D-glucosamine + 2,6-bis(N-acetyl-beta-D-glucosaminyl)-alpha-D-mannosyl-R UDP + 2,4,6-tris(N-acetyl-beta-D-glucosaminyl)-alpha-D-mannosyl-R
R represents the remainder of the N-linked oligosaccharide in the glycoprotein acceptor.
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