All-trans-nonaprenyl diphosphate synthase (geranylgeranyl-diphosphate specific)

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Template:Short description Template:Infobox enzyme All-trans-nonaprenyl diphosphate synthase (geranylgeranyl-diphosphate specific) (Template:EC number, nonaprenyl diphosphate synthase, solanesyl diphosphate synthase, At-SPS2, At-SPS1, SPS1, SPS2) is an enzyme with systematic name geranylgeranyl-diphosphate:isopentenyl-diphosphate transtransferase (adding 5 isopentenyl units).[1][2][3] This enzyme catalyses the following chemical reaction

geranylgeranyl diphosphate + 5 isopentenyl diphosphate 5 diphosphate + all-trans-nonaprenyl diphosphate

Geranylgeranyl diphosphate is preferred over farnesyl diphosphate as allylic substrate.

In 2020, aclonifen was shown to inhibit the enzyme and is the first compound to have this mechanism of action as a herbicide.[4]

References

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Template:Alkyl and aryl transferases Template:Enzymes Template:Portal bar