Aliphatic nitrilase

Template:Short description Template:Infobox enzyme In enzymology, an aliphatic nitrilase also known as aliphatic nitrile aminohydrolase (Template:EC number) is an enzyme that catalyzes the hydrolysis of nitriles to carboxylic acids:

R-CN + 2 H₂O $\rightleftharpoons$ R-COOH + NH₃

Thus, the two substrates of this enzyme are an aliphatic nitrile (R-CN) and H₂O, whereas its two products are a carboxylic acid (R-COOH) and NH₃.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in nitriles. This enzyme participates in styrene degradation.

References

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