Agmatine deiminase

Template:Short description Template:Infobox enzyme In enzymology, an agmatine deiminase (Template:EC number) is an enzyme that catalyzes the chemical reaction

agmatine + H₂O $\rightleftharpoons$ N-carbamoylputrescine + NH₃

Thus, the two substrates of this enzyme are agmatine and H₂O, whereas its two products are N-carbamoylputrescine and NH₃.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amidines. The systematic name of this enzyme class is agmatine iminohydrolase. This enzyme is also called agmatine amidinohydrolase. This enzyme participates in urea cycle and metabolism of amino groups.

Structural studies

As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes Template:PDB link, Template:PDB link, Template:PDB link, and Template:PDB link.

References

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