Adenosylcobinamide-phosphate guanylyltransferase

Template:Short description Template:Infobox enzyme In enzymology, an adenosylcobinamide-phosphate guanylyltransferase (Template:EC number) is an enzyme that catalyzes the chemical reaction

GTP + adenosylcobinamide phosphate $\rightleftharpoons$ diphosphate + adenosylcobinamide-GDP

The two substrates of this enzyme are GTP and adenosylcobinamide phosphate; its two products are diphosphate and adenosylcobinamide-GDP.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is GTP:adenosylcobinamide-phosphate guanylyltransferase. Other names in common use include CobU, adenosylcobinamide kinase/adenosylcobinamide-phosphate, guanylyltransferase, and AdoCbi kinase/AdoCbi-phosphate guanylyltransferase. This enzyme is part of the biosynthetic pathway to cobalamin (vitamin B₁₂) in bacteria.

See also

• Cobalamin biosynthesis

References

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