AMP nucleosidase

Template:Infobox enzyme In enzymology, an AMP nucleosidase (Template:EC number) is an enzyme that catalyzes the chemical reaction

AMP + H₂O $\rightleftharpoons$ D-ribose 5-phosphate + adenine

Thus, the two substrates of this enzyme are AMP and H₂O, whereas its two products are D-ribose 5-phosphate and adenine.

This enzyme belongs to the family of hydrolases, specifically those glycosylases that hydrolyse N-glycosyl compounds. The systematic name of this enzyme class is AMP phosphoribohydrolase. Other names in common use include adenylate nucleosidase, and adenosine monophosphate nucleosidase. This enzyme participates in purine metabolism.

Structural studies

As of late 2007, 5 structures have been solved for this class of enzymes, with PDB accession codes Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, and Template:PDB link.

References

• Template:Cite journal

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