A-1,6-mannosyl-glycoprotein 2-b-N-acetylglucosaminyltransferase

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Template:Short description Template:Infobox enzyme Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Template:EC number, N-acetylglucosaminyltransferase II, N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II, acetylglucosaminyltransferase II, uridine diphosphoacetylglucosamine-mannoside alpha1->6-acetylglucosaminyltransferase, uridine diphosphoacetylglucosamine-alpha-1,6-mannosylglycoprotein beta-1-2-N-acetylglucosaminyltransferase, uridine diphosphoacetylglucosamine-alpha-D-mannoside beta1-2-acetylglucosaminyltransferase, UDP-GlcNAc:mannoside alpha1-6 acetylglucosaminyltransferase, alpha-1,6-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase, GnTII) is an enzyme with systematic name UDP-N-acetyl-D-glucosamine:6-(alpha-D-mannosyl)-beta-D-mannosyl-glycoprotein 2-beta-N-acetyl-D-glucosaminyltransferase.[1][2][3][4][5] This enzyme catalyses the following chemical reaction

UDP-N-acetyl-D-glucosamine + 6-(alpha-D-mannosyl)-beta-D-mannosyl-R ⇌ UDP + 6-(2-[N-acetyl-beta-D-glucosaminyl]-alpha-D-mannosyl)-beta-D-mannosyl-R

R represents the remainder of the N-linked oligosaccharide in the glycoprotein acceptor.

References

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Template:Glycosyltransferases Template:Enzymes Template:Portal bar

  1. ↑ Template:Cite journal
  2. ↑ Template:Cite journal
  3. ↑ Template:Cite journal
  4. ↑ Template:Cite journal
  5. ↑ Template:Cite book
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