6-Hydroxy-3-succinoylpyridine 3-monooxygenase

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Template:Short description Template:Infobox enzyme 6-hydroxy-3-succinoylpyridine 3-monooxygenase (Template:EC number, 6-hydroxy-3-succinoylpyridine hydroxylase, hspA (gene), hspB (gene)) is an enzyme with systematic name 4-(6-hydroxypyridin-3-yl)-4-oxobutanoate,NADH:oxygen oxidoreductase (3-hydroxylating, succinate semialdehyde releasing).[1][2] This enzyme catalyses the following chemical reaction

4-(6-hydroxypyridin-3-yl)-4-oxobutanoate + 2 NADH + 2 H+ + O2 ⇌ 2,5-dihydroxypyridine + succinate semialdehyde + 2 NAD+ + H2O

6-hydroxy-3-succinoylpyridine 3-monooxygenase catalyses a reaction in the nicotine degradation pathway of Pseudomonas species.

References

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Template:Dioxygenases Template:Enzymes Template:Portal bar

  1. ↑ Template:Cite journal
  2. ↑ Template:Cite journal
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