5-carboxymethyl-2-hydroxymuconate Delta-isomerase
Template:Short description Template:Infobox enzyme In enzymology, a 5-carboxymethyl-2-hydroxymuconate Delta-isomerase (Template:EnzExplorer) is an enzyme that catalyzes the chemical reaction
- 5-carboxymethyl-2-hydroxymuconate 5-carboxy-2-oxohept-3-enedioate
Hence, this enzyme has one substrate, 5-carboxymethyl-2-hydroxymuconate, and one product, 5-carboxy-2-oxohept-3-enedioate.
This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases transposing C=C bonds. The systematic name of this enzyme class is 5-carboxymethyl-2-hydroxymuconate Delta2,Delta4-2-oxo,Delta3-isomerase. This enzyme participates in tyrosine metabolism and benzoate degradation via hydroxylation.
Structural studies
As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes Template:PDB link, Template:PDB link, Template:PDB link, and Template:PDB link.
References
Template:Intramolecular oxidoreductases Template:Enzymes Template:Portal bar