4-hydroxybenzoyl-CoA reductase

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Template:Enzyme In enzymology, a 4-hydroxybenzoyl-CoA reductase (Template:EC number) is an enzyme found in some bacteria and archaea that catalyzes the chemical reaction[1][2]

benzoyl-CoA + acceptor + H2O 4-hydroxybenzoyl-CoA + reduced acceptor

The 3 substrates of this enzyme are benzoyl-CoA, acceptor, and H2O, whereas its two products are 4-hydroxybenzoyl-CoA and reduced acceptor.

This enzyme participates in benzoate degradation via coa ligation.

Nomenclature

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with other acceptors. The systematic name of this enzyme class is benzoyl-CoA:acceptor oxidoreductase. Other names in common use include:

  • 4-hydroxybenzoyl-CoA reductase (dehydroxylating), and
  • 4-hydroxybenzoyl-CoA:(acceptor) oxidoreductase.

References

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Further reading

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