4-hydroxy-4-methyl-2-oxoglutarate aldolase
Template:Short description Template:Infobox enzyme The enzyme 4-hydroxy-4-methyl-2-oxoglutarate aldolase (Template:EnzExplorer) catalyzes the chemical reaction
- 4-hydroxy-4-methyl-2-oxoglutarate 2 pyruvate
This enzyme belongs to the family of lyases, specifically the oxo-acid-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 4-hydroxy-4-methyl-2-oxoglutarate pyruvate-lyase (pyruvate-forming). Other names in common use include pyruvate aldolase, gamma-methyl-gamma-hydroxy-alpha-ketoglutaric aldolase, 4-hydroxy-4-methyl-2-ketoglutarate aldolase, and 4-hydroxy-4-methyl-2-oxoglutarate pyruvate-lyase. This enzyme participates in benzoate degradation via hydroxylation and c5-branched dibasic acid metabolism.
References
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- Template:Cite journal
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- Boyer, P.D. (Ed.), The Enzymes, 3rd ed., vol. 7, Academic Press, New York, 1972, p. 281-302.
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