4-chlorobenzoate dehalogenase

Template:Short description Template:Infobox enzyme In enzymology, a 4-chlorobenzoate dehalogenase (Template:EC number) is an enzyme that catalyzes the chemical reaction

4-chlorobenzoate + H₂O $\rightleftharpoons$ 4-hydroxybenzoate + chloride

Thus, the two substrates of this enzyme are 4-chlorobenzoate and H₂O, whereas its two products are 4-hydroxybenzoate and chloride.

This enzyme belongs to the family of hydrolases, specifically those acting on halide bonds in carbon-halide compounds. The systematic name of this enzyme class is 4-chlorobenzoate chlorohydrolase. This enzyme is also called halobenzoate dehalogenase.

Structural studies

As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes Template:PDB link, Template:PDB link, and Template:PDB link.

References

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