4-chlorobenzoate—CoA ligase
Template:Short description Template:Infobox enzyme In enzymology, a 4-chlorobenzoate—CoA ligase (Template:EnzExplorer) is an enzyme that catalyzes the chemical reaction
- 4-chlorobenzoate + CoA + ATP 4-chlorobenzoyl-CoA + AMP + diphosphate
The 3 substrates of this enzyme are 4-chlorobenzoate, CoA, and ATP, whereas its 3 products are 4-chlorobenzoyl-CoA, AMP, and diphosphate.
This enzyme belongs to the family of ligases, specifically those forming carbon-sulfur bonds as acid-thiol ligases. The systematic name of this enzyme class is 4-chlorobenzoate:CoA ligase. This enzyme participates in 2,4-dichlorobenzoate degradation. It employs one cofactor, magnesium.
Structural studies
As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes Template:PDB link and Template:PDB link.
References
Template:Ligases CO CS and CN Template:Enzymes Template:Portal bar