3beta-hydroxy-5alpha-steroid dehydrogenase
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Template:Short description Template:Infobox enzyme Template:More footnotes needed In enzymology, a 3β-hydroxy-5α-steroid dehydrogenase (Template:EC number) is an enzyme that catalyzes the chemical reaction
- 3β-hydroxy-5α-pregnane-20-one + NADP+ 5α-pregnan-3,20-dione + NADPH + H+
Thus, the two substrates of this enzyme are 3β-hydroxy-5α-pregnane-20-one (allopregnanolone) and NADP+, whereas its 3 products are 5α-pregnan-3,20-dione, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 3β-hydroxy-5α-steroid:NADP+ 3-oxidoreductase.
References
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