3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase

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Template:Short description Template:Infobox enzyme The enzyme 3α,7α,12α-trihydroxy-5β-cholest-24-enoyl-CoA hydratase (Template:EnzExplorer) catalyzes the chemical reaction

(24R,25R)-3α,7α,12α,24-tetrahydroxy-5β-cholestanoyl-CoA ⇌
(24E)-3α,7α,12α-trihydroxy-5β-cholest-24-enoyl-CoA + H2O

Nomenclature

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is (24R,25R)-3α,7α,12α,24-tetrahydroxy-5beta-cholestanoyl-CoA hydro-lyase [(24E)-3α,7α,12α-trihydroxy-5β-cholest-24-enoyl-CoA-forming]. Other names in common use include 46 kDa hydratase 2, and (24R,25R)-3α,7α,12α,24-tetrahydroxy-5β-cholestanoyl-CoA hydro-lyase.

References

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Further reading

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