3-oxoadipyl-CoA thiolase

Template:Short description Template:Infobox enzyme In enzymology, a 3-oxoadipyl-CoA thiolase (Template:EC number) is an enzyme that catalyzes the chemical reaction

succinyl-CoA + acetyl-CoA $\rightleftharpoons$ CoA + 3-oxoadipyl-CoA

Thus, the two substrates of this enzyme are succinyl-CoA and acetyl-CoA, whereas its two products are CoA and 3-oxoadipyl-CoA.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is succinyl-CoA:acetyl-CoA C-succinyltransferase. This enzyme participates in benzoate degradation via hydroxylation.

3-Oxoadipyl-CoA thiolase belongs to the thiolase family of enzymes.

References

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• Template:Cite journal

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