3-hydroxypimeloyl-CoA dehydrogenase

Template:Short description Template:Infobox enzyme In enzymology, a 3-hydroxypimeloyl-CoA dehydrogenase (Template:EC number) is an enzyme that catalyzes the chemical reaction

3-hydroxypimeloyl-CoA + NAD⁺ $\rightleftharpoons$ 3-oxopimeloyl-CoA + NADH + H⁺

Thus, the two substrates of this enzyme are 3-hydroxypimeloyl-CoA and NAD⁺, whereas its 3 products are 3-oxopimeloyl-CoA, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is 3-hydroxypimeloyl-CoA:NAD⁺ oxidoreductase. This enzyme participates in benzoate degradation via coa ligation.

References

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