3-Isopropylmalate dehydrogenase

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Template:Short description Template:Infobox enzyme 3-Isopropylmalate dehydrogenase (Template:EC number) is an enzyme that is a part of the isopropylmalate dehydrogenase family, which catalyzes the chemical reactions:[1][2][3][4]

(2R,3S)-3-isopropylmalate + NAD+ ⇌ 4-methyl-2-oxopentanoate + CO2 + NADH
(2R,3S)-3-isopropylmalate + NAD+ ⇌ (2S)-2-isopropyl-3-oxosuccinate + H+ + NADH
(2S)-2-isopropyl-3-oxosuccinate + H+ ⇌ 4-methyl-2-oxopentanoate + CO2

References

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  1. ↑ Template:Cite journal
  2. ↑ Template:Cite journal
  3. ↑ Template:Cite journal
  4. ↑ Template:Cite journal
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