3,5,7-Trioxododecanoyl-CoA synthase

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Template:Short description Template:Infobox enzyme 3,5,7-Trioxododecanoyl-CoA synthase (Template:EC number, TKS) is an enzyme with systematic name malonyl-CoA:hexanoyl-CoA malonyltransferase (3,5,7-trioxododecanoyl-CoA-forming).[1][2] This enzyme catalyses the following chemical reaction

3 malonyl-CoA + hexanoyl-CoA 3 CoA + 3,5,7-trioxododecanoyl-CoA + 3 CO2

This polyketide synthase catalyse the first step in the cannabinoids biosynthetic pathway of the plant Cannabis sativa.

References

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