2-oxoglutarate decarboxylase

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Template:Short description Template:Infobox enzyme The enzyme 2-oxoglutarate decarboxylase (Template:EnzExplorer) catalyzes the chemical reaction: 2-oxoglutarate succinate semialdehyde + CO2

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 2-oxoglutarate carboxy-lyase (succinate-semialdehyde-forming). Other names in common use include oxoglutarate decarboxylase, alpha-ketoglutarate decarboxylase, alpha-ketoglutaric decarboxylase, oxoglutarate decarboxylase, pre-2-oxoglutarate decarboxylase, and 2-oxoglutarate carboxy-lyase. It employs one cofactor, thiamin diphosphate.

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