2,6-dioxo-6-phenylhexa-3-enoate hydrolase

Template:Short description Template:Infobox enzyme In enzymology, a 2,6-dioxo-6-phenylhexa-3-enoate hydrolase (Template:EC number) is an enzyme that catalyzes the chemical reaction

2,6-dioxo-6-phenylhexa-3-enoate + H₂O $\rightleftharpoons$ benzoate + 2-oxopent-4-enoate

Thus, the two substrates of this enzyme are 2,6-dioxo-6-phenylhexa-3-enoate and H₂O, whereas its two products are benzoate and 2-oxopent-4-enoate.

This enzyme belongs to the family of hydrolases, specifically those acting on carbon-carbon bonds in ketonic substances. The systematic name of this enzyme class is 2,6-dioxo-6-phenylhexa-3-enoate benzoylhydrolase. This enzyme is also called HOHPDA hydrolase. This enzyme participates in biphenyl degradation and fluorene degradation.

Structural studies

As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes Template:PDB link, Template:PDB link, and Template:PDB link.

References

• Template:Cite journal

Template:Hydrolase-stub