2,4-Dichlorobenzoyl-CoA reductase

Template:Infobox enzyme In enzymology, a 2,4-dichlorobenzoyl-CoA reductase (Template:EC number) is an enzyme that catalyzes the chemical reaction

4-chlorobenzoyl-CoA + NADP⁺ + HCl $\rightleftharpoons$ 2,4-dichlorobenzoyl-CoA + NADPH + H⁺

The 3 substrates of this enzyme are 4-chlorobenzoyl-CoA, NADP⁺, and HCl, whereas its 3 products are 2,4-dichlorobenzoyl-CoA (the thioester of 2,4-dichlorobenzoic acid), NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 4-chlorobenzoyl-CoA:NADP+ oxidoreductase (halogenating). This enzyme participates in degradation of 2,4-dichlorobenzoate.

References

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