1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase
Template:Short description Template:Infobox enzyme In enzymology, a 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase (Template:EC number) is an enzyme that catalyzes the chemical reaction
- (1R,6R)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate + NADTemplate:Sup catechol + COTemplate:Sub + NADH + HTemplate:Sup
Thus, the two substrates of this enzyme are (1R,6R)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate and [[nicotinamide adenine dinucleotide|NADTemplate:Sup]], whereas its 4 products are catechol, [[carbon dioxide|COTemplate:Sub]], NADH, and [[hydrogen ion|HTemplate:Sup]].
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (1R,6R)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate:NAD+ oxidoreductase (decarboxylating). Other names in common use include 3,5-cyclohexadiene-1,2-diol-1-carboxylate dehydrogenase, 3,5-cyclohexadiene-1,2-diol-1-carboxylic acid dehydrogenase, dihydrodihydroxybenzoate dehydrogenase, DHBDH, cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate dehydrogenase, 2-hydro-1,2-dihydroxybenzoate dehydrogenase, cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate:NAD+, oxidoreductase, and dihydrodihydroxybenzoate dehydrogenase. This enzyme participates in benzoate degradation via hydroxylation and benzoate degradation via coa ligation.
References
Template:CH-CH oxidoreductases Template:Enzymes Template:Portal bar