(butirosin acyl-carrier protein)—L-glutamate ligase

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Template:Short description Template:Infobox enzyme (Butirosin acyl-carrier protein)—L-glutamate ligase (Template:EnzExplorer, [BtrI acyl-carrier protein]—L-glutamate ligase, BtrJ) is an enzyme with systematic name (BtrI acyl-carrier protein):L-glutamate ligase (ADP-forming).[1] This enzyme catalyses the following chemical reaction

(1) ATP + L-glutamate + BtrI acyl-carrier protein ⇌ ADP + phosphate + L-glutamyl-[BtrI acyl-carrier protein]
(2) ATP + L-glutamate + 4-amino butanoyl-[BtrI acyl-carrier protein] ⇌ ADP + phosphate + 4-(gamma-L-glutamylamino)butanoyl-[BtrI acyl-carrier protein]

This enzyme catalyses two steps in the biosynthesis of the side chain of the aminoglycoside antibiotics of the butirosin family.

References

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Template:Ligases CO CS and CN Template:Enzymes Template:Portal bar

  1. ↑ Template:Cite journal
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