(S)-2-hydroxy-acid oxidase
Template:Short description Template:Infobox enzyme In enzymology, an (S)-2-hydroxy-acid oxidase (Template:EC number) is an enzyme that catalyzes the chemical reaction
- (S)-2-hydroxy acid + OTemplate:Sub 2-oxo acid + HTemplate:SubOTemplate:Sub
Thus, the two substrates of this enzyme are (S)-2-hydroxy acid and [[oxygen|OTemplate:Sub]], whereas its two products are 2-oxo acid and [[hydrogen peroxide|HTemplate:SubOTemplate:Sub]].
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with oxygen as acceptor. The systematic name of this enzyme class is (S)-2-hydroxy-acid:oxygen 2-oxidoreductase. Other names in common use include glycolate oxidase, hydroxy-acid oxidase A, hydroxy-acid oxidase B, oxidase, L-2-hydroxy acid, hydroxyacid oxidase A, L-alpha-hydroxy acid oxidase, and L-2-hydroxy acid oxidase. This enzyme participates in glyoxylate and dicarboxylate metabolism. It employs one cofactor, FMN.
Structural studies
As of late 2007, 5 structures have been solved for this class of enzymes, with PDB accession codes Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, and Template:PDB link.
References
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