(3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate dehydrogenase

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Template:Short description Template:Infobox enzyme In enzymology, a (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate dehydrogenase (Template:EC number) is an enzyme that catalyzes the chemical reaction

(3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate + NADTemplate:Sup ⇌ 3,4-dihydroxybenzoate + COTemplate:Sub + NADH

Thus, the two substrates of this enzyme are (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate and [[nicotinamide adenine dinucleotide|NADTemplate:Sup]], whereas its 3 products are 3,4-dihydroxybenzoate, [[carbon dioxide|COTemplate:Sub]], and NADH.

This enzyme is a part of the terephthalate degradation pathway in bacteria.[1]

Family

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate:NAD+ oxidoreductase. Another name in common use is (1R,2S)-dihydroxy-3,5-cyclohexadiene-1,4-dicarboxylate dehydrogenase. This enzyme employs one cofactor, iron.

References

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Template:CH-CH oxidoreductases Template:Enzymes Template:Portal bar


Template:1.3-enzyme-stub

  1. ↑ Template:Cite web
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