2-oxoglutarate decarboxylase

Template:Short description Template:Infobox enzyme The enzyme 2-oxoglutarate decarboxylase (Template:EnzExplorer) catalyzes the chemical reaction: 2-oxoglutarate $\rightleftharpoons$ succinate semialdehyde + CO₂

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 2-oxoglutarate carboxy-lyase (succinate-semialdehyde-forming). Other names in common use include oxoglutarate decarboxylase, alpha-ketoglutarate decarboxylase, alpha-ketoglutaric decarboxylase, oxoglutarate decarboxylase, pre-2-oxoglutarate decarboxylase, and 2-oxoglutarate carboxy-lyase. It employs one cofactor, thiamin diphosphate.

References

• Template:Cite journal

Template:4.1-enzyme-stub