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...overage''' (or depth) is the number of unique reads that include a given [[nucleotide]] in the reconstructed sequence.<ref>{{Cite web|url=http://www.illumina.com ...cing errors. Furthermore, many positions in a genome contain rare [[single-nucleotide polymorphism]]s (SNPs). Hence to distinguish between sequencing errors and ...

...cial experimental methods based on known population-wide single nucleotide polymorphisms (see [[SNP genotyping]]). Due to the increasing abundance of NGS data, thes ...e population, in which case they may be referred to as [[single nucleotide polymorphisms]] (SNPs). Technically the term SNP only refers to these kinds of variations ...

...m/science/article/pii/S1674205224003903 }}</ref> In this context, the four nucleotide bases—adenine (A), guanine (G), cytosine (C), and thymine (T)—are analogous ...o model complex genomic interactions by leveraging upstream and downstream nucleotide contexts. ...

...ponential dispersion model for the distribution of human single nucleotide polymorphisms | journal = Mol Biol Evol | volume = 20 | issue = 4| pages = 579–590 | doi= ...

...variants to a trait. GCTA is typically applied to common single nucleotide polymorphisms ([[SNPs]]) on a genotyping array (or "chip") and thus termed "chip" or "SNP Most frequently, GCTA is run with a single relatedness matrix constructed from common SNPs and will not capture (or no ...

...A sequences. In some cases the term "zygosity" is used in the context of a single chromosome.<ref>{{Cite journal |last=Carr |first=Martin |last2=Cotton |firs ...leles at a locus, ''hemizygous'' describes a genotype consisting of only a single copy of a particular gene in an otherwise diploid organism, and ''nullizygo ...

...M. J. | s2cid = 2813666}}</ref> The identification of associated [[single-nucleotide polymorphism]]s (variation of a DNA sequence in a population) underpin GWA Whilst the single-gene, single-disease hypothesis holds for Mendelian disorders such as [[Huntington's dis ...

...tes of thousands of individual genetic variants (i.e., [[single-nucleotide polymorphisms]], or SNPs). ...ion with odds for disease that are significantly greater than when using a single polymorphism.]] ...

...the assumption of a single uniform rate is an oversimplification. Though a single mutation rate is often applied, it is often a composite or an average of se ...2009}} consider both coding and non-coding region mutations to arrive at a single mutation rate, but apply a correction factor to account for selection in th ...

...solves the problem of the undetectable, small changes in the expression of single genes.<ref>{{cite journal | vauthors = Maleki F, Ovens K, Hogan DJ, Kusalik ...richment analysis for multiple gene list using multiple source database in single run, retrieve or download complete GO terms/Pathways/Functions with associa ...

...ponential dispersion model for the distribution of human single nucleotide polymorphisms | journal = Mol Biol Evol | volume = 20 | issue = 4| pages = 579–590 | doi= ...scribed what is now known as Taylor's law, but in the context of data from single species. ...

...yping|genotype]] the [[Nucleic acid sequence|sequence]] of human [[DNA]] [[nucleotide]]s.<ref name="Lander2011">{{cite journal | vauthors = Lander ES | title = I ...the relationship of millions of [[Polymorphism (biology)#Genetics|genetic polymorphisms]] with behavioural phenotypes across the [[genome]].<ref name="McCarthyAbec ...

...fications]], [[CO₂ retention|CO₂ retaining variants]], [[single-nucleotide polymorphism]]s and [[copy number variant]]s should be expanded in order to ...n]] (Figure 1) revealed [[choroidal fold]]s below the [[optic disc]] and a single [[Cotton wool spots|cotton-wool spot]] in the inferior arcade of the right ...