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...dyl transferase center confers resistance to an array of protein synthesis inhibitors | journal = Journal of Molecular Biology | volume = 380 | issue = 4 | pages ...

...0x450px|Enzymatic reaction catalyzed by DHOQO. In green is represented the protein surface, sitting in the membrane (in gray)|thumb]] ...-tagged rat and human flavoenzyme dihydroorotate dehydrogenase | journal = Protein Expression and Purification | volume = 13 | issue = 3 | pages = 414–22 | da ...

...day has 7 kinds of different PLM from PLM A to PLM G which differ the post-synthesis from the biosynthesis of PLM. ...acteria and fungi. From the PLM B, there are many articles wrote about the synthesis of different PLM A through PLM G. ...

...ein-1: unique structural features with functional implications | journal = Protein Science | volume = 14 | issue = 8 | pages = 1964–74 | date = Aug 2005 | pmi ...d [[propargylamine]]. However, hydrazines are weak inhibitors and stronger inhibitors have been developed. ...

...ong-chain fatty acid biosynthesis by mefluidide and perfluidone, selective inhibitors of 3-ketoacyl-CoA synthases | journal = Phytochemistry | volume = 76 | page ...s context refers, for example, to the C26 [[fatty acid]]s involved in the synthesis of [[phospholipid]]s and [[ceramide]]s.<ref name=Oh /> ...

...orescence|fluorescent]] [[molecule]] that is able to determine whether a [[protein]] binds to [[Adenosine triphosphate|ATP]], and the constants associated wit ...used to drive biological machinery and regulate a number of processes via protein-[[phosphorylation]].<ref name=":1" /> However, the proteins that bind ATP f ...

{{Infobox protein family ..., Birck MR, Woodard RW, Gatti DL | title = Structure-based design of novel inhibitors of 3-deoxy-D-manno-octulosonate 8-phosphate synthase | journal = Drug Desig ...

...never both at the same time.<ref name="NIH CTT" /> For example, allosteric inhibitors may display competitive, [[non-competitive inhibition|non-competitive]], or ...ctive site. The active site is a region on an enzyme to which a particular protein or substrate can bind. The active site will thus only allow one of the two ...

...es or the promotion of [[Biological functions of nitric oxide|nitric oxide synthesis]] (NOS) activity. The resulting nitric oxide formation reacts with [[supero # formation of protein [[adduct]]s inhibiting epigenetic regulation ...

...r a human enzyme that hydrolyzes 8-oxo-dGTP, a mutagenic substrate for DNA synthesis | journal = The Journal of Biological Chemistry | volume = 268 | issue = 31 ...|date=2017-10-12|title=Fragment-Based Discovery and Optimization of Enzyme Inhibitors by Docking of Commercial Chemical Space|journal=Journal of Medicinal Chemis ...

...he active site of [NiFe] hydrogenase in the oxidized form. L refers to non-protein ligand (1 C≡O and 2 ⁻C≡N). X can be an [[oxide]], [[sulfur]], [[ ...xidation state.<ref name="ChiouCRC" /> The exact geometry of the three non-protein [[ligands]] (denoted as L) coordinating to the Fe ion is not known; however ...

...ips, medical devices must be kept sanitary, etc. Although chemical fouling inhibitors, metallic coatings, and cleaning processes can be used to reduce fouling, n ...e=Brault /> therefore film thickness becomes an important parameter in the synthesis of ultra-low fouling surfaces. Film thickness is determined by three factor ...

...=JJ |title=Bigger, Better, Faster: Principles and Models of AKAP Anchoring Protein Signaling |volume=58 |issue=5 |pages=462–9 |doi=10.1097/FJC.0b013e31822001e ...ration of the effector to produce larger changes in the amount of modified protein. This amplification provided added sensitivity in biological control, and i ...

...binding leads to loss-of-function of the protein, and/or breakdown of the protein into nonfunctional portions. ===Viral inhibitors=== ...

...area of chemistry where it was originally defined: in practical [[organic synthesis|synthetic]] studies of the outcome of carbon-carbon bond-forming reactions ...land, D.E. | year = 2002 | title = A clogged gutter mechanism for protease inhibitors | journal = Proc. Natl. Acad. Sci. USA | volume = 99 | issue = 16 | pages = ...

...ution therapy with [[selenium]], a trace element that is essential for the synthesis of deiodinases.<ref name="Krysiak_Selenomethionine_Men_2018">{{cite journal ...cts it correlates (negatively) with age and concentrations of [[c-reactive protein]], [[troponin T]] and [[Brain natriuretic peptide 32|B-type natriuretic pep ...

...roteins, and their interactions and functions are complicated by diverse [[protein subunit|subunit]] compositions and regulation by conserved cellular signals * [[G protein-coupled inwardly-rectifying potassium channel|GIRK]]: [[channel opener]] ...

...ridge, Massachusetts}}</ref>). A 1988 network became state of the art in [[protein structure prediction]], an early application of deep learning to bioinforma ...ecurrent Neural Network with Recurrent Output Layer for Low-Latency Speech Synthesis |url=https://static.googleusercontent.com/media/research.google.com/en//pub ...