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{{Infobox protein family | OPM protein = ...

..., a fragment structure (represented by a "paradigm" fragment chosen from a protein in the PDB) and optionally, a 4-dimensional tensor of pairwise sequence cov ...ach family contained a single known structure (parent) from the Brookhaven protein Data Bank. These were a subset of the PDBSelect-25 list, having no more tha ...

Human protein [[DTYMK]] contains this domain. ...structure|structures]] have been solved for this class of enzymes, with [[Protein Data Bank|PDB]] accession codes {{PDB link|1E2D}}, {{PDB link|1E2E}}, {{PDB ...

...linked. In simpler terms, it helps scientists understand which parts of a protein are working together and how they have changed over evolutionary time.<ref> ...Ranganathan group] on the [[GPCR]], [[serine protease]] and [[hemoglobin]] families also showed energetic coupling in sparse networks of residues that cooperat ...

This article discusses the protein domains that make up the SAM synthetase enzyme and how these domains contri ...Roth A, Washietl S, Wen J, Kellis M, Breaker R, Pedersen JS | title = New families of human regulatory RNA structures identified by comparative analysis of ve ...

...erase superfamily with a large set of manually-annotated proteins |journal=Protein Sci. Biochem. | year=2022 |volume= 31 |issue= 4 |pages= 864–881 |pmid=35049 ==Families== ...

...essible surface area''' or '''relative solvent accessibility (RSA)''' of a protein residue is a measure of [[Solvent exposure|residue solvent exposure]]. It c ASA and hence RSA values are generally calculated from a protein structure, for example with the software DSSP.<ref name = "DSSP"> ...

...ns</math> 3-O-beta-D-galactosyl-N-acetyl-alpha-D-galactosamine + L-serine-[protein] ...de hydrolases: subfamily structure and evolutionary connections with other families | journal = Journal of Bioinformatics and Computational Biology | volume = ...

...title = Role of cysteine residues in pseudouridine synthases of different families | journal = Biochemistry | volume = 38 | issue = 40 | pages = 13106–11 | da ...

...alysis of residue coevolution captures native contacts across many protein families|journal=Proceedings of the National Academy of Sciences|date=21 November 20 ...20714458 |issn=0036-8075}}</ref> and the modeling of [[Molecular evolution|protein evolution]].<ref>{{Cite journal |last1=Rodriguez-Rivas |first1=Juan |last2= ...

...E'')}} that is in any nontrivial [[Minor (graph theory)#Minor-closed graph families|minor-closed graph family]] (e.g., a [[planar graph]]), if {{mvar|G}} conta ...e <math>2^{O(k)}</math>. Consequently, by composing the {{mvar|k}}-perfect families from both steps, a {{mvar|k}}-perfect family of size <math>2^{O(k)}\log |V| ...

...ene.<ref name="Graur_2000" /> It is much more rare to see major changes in protein function, such as subunit structure or substrate and ligand affinity, as a ...a vivid example of neofunctionalization. The development of an antifreeze protein from an ancestral Sialic Acid Synthase (SAS) gene illustrates the acquisiti ...

...probabilistic suffix trees: statistical modeling and prediction of protein families |journal = Bioinformatics |volume = 17|issue = 5|date = 2001|pages = 23–43 ...

{{Redirect|Root symbol|the root symbols for gene and protein families|Gene nomenclature#Symbol and name}} ...

...ix multiplication and applications of mathematics to biology, particularly protein folding."<ref>{{cite web|title=Sandy Davie's Home page|website=School of Ma ...al|doi=10.1016/0167-2789(93)90047-5|title=Period-doubling in two-parameter families|year=1993|last1=Davie|first1=A.M.|last2=Dutta|first2=T.K.|journal=Physica D ...

| OPM protein= ...=en |doi=10.1007/978-3-0348-8446-4_2 |isbn=978-3-0348-8446-4}}</ref> These families are not similar in sequence or structure because they evolved independently ...

...aloop]] is a four-base pairs hairpin RNA structure. There are three common families of tetraloop in ribosomal RNA: '''UNCG''', '''GNRA''', and '''CUUG''' (''N' The quaternary structure of nucleic acids is similar to that of [[protein quaternary structure]]. Although some of the concepts are not exactly the s ...

...7" /> DEC2 inhibits [[CLOCK]]/[[BMAL1]] activation of PER, through protein-protein interaction or competition for the [[E-box]] transcriptional elements.<ref ...caused a short sleep phenotype. NPSR1 is a [[G protein-coupled receptor|G-protein coupled receptor]] that plays a role in [[arousal]] and sleep behaviors. Th ...

...emical Technology |access-date=22 October 2015}}</ref> structural biology, protein dynamics,<ref>{{cite news |date=30 April 2015 |title=Waking proteins up fro ...equency pulses for homonuclear decoupling in solid-state NMR, allowing new families of decoupling sequences.<ref>{{cite journal |last1=Sakellariou |first1=Dimi ...

...anson J, Paliwal K, Zhou Y | title = Sixty-five years of the long march in protein secondary structure prediction: the final stretch? | journal = Briefings in * Comparing and aligning RNA, protein, and DNA sequences. ...