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{{Pharmacology}} [[Category:Clinical pharmacology]] ...

The accumulation ratio of a specific drug in humans is determined by [[clinical studies]]. According to a 2013 analysis, such studies are typically done wi ...02113149990002|title=Systematic Evaluation of Dose Accumulation Studies in Clinical Pharmacokinetics|year=2013|last1=Li|first1=Lujin|last2=Li|first2=Xianxing|l ...

...te points in time and the [[trapezoidal rule]] is used to estimate AUC. In pharmacology, the area under the plot of plasma concentration of a drug ''versus'' time ...or Optimal Dosing for Gram-Negative Infections: An Updated Review |journal=Clinical Pharmacokinetics |volume=61 |issue=8 |pages=1075–1094 |doi=10.1007/s40262-0 ...

== Pharmacology == ...effectiveness and safety have been investigated and documented in numerous clinical studies and in various patient populations.<ref name=Toblli2007/> This has ...

...a number of processes by which a drug is eliminated (that is, [[clearance (pharmacology)|cleared]] and [[excretion|excreted]]) from an organism either in an unalte ...ioning [[hepatocyte]]s, this is the reason that [[liver failure]] has such clinical importance. ...

...d treatment, but current techniques using CED have failed to progress past clinical trials due to a variety of physical limitations associated with CED itself. ...ment of the catheter used to deliver the drugs. A vast majority of current clinical studies using CED are currently using CED as a method to treat [[brain tumo ...

...begron is in phase 2b clinical trials to treat OAB in women and in phase 1 clinical trials in men to treat OAB.<ref name=":6">{{Cite news|url=https://clinicalt ...first2=Erika|date=August 2015|title=A Review of Nebivolol Pharmacology and Clinical Evidence|journal=Drugs|language=en|volume=75|issue=12|pages=1349–1371|doi=1 ...

== Clinical significance == ...iabetes-Related Morbidity and Mortality in the General Population |journal=Clinical Thyroidology |date=April 2019 |volume=31 |issue=4 |pages=138–140 |doi=10.10 ...

...of threshold dose in risk assessment safeguards the participants in human clinical trials and evaluates the risks of chronic exposure to certain substances.<r ...of a substance that has no observable effect on the treated group in human clinical trials or animal experimental trials.<ref name=":1" /> In some literature, ...

...s|first1=Eric|last2=Korbonits|first2=Marta|last3=Romijn|first3=J. A.|title=Clinical Neuroendocrinology|date=2014|publisher=Elsevier|isbn=978-0-444-62612-7|page == Clinical significance == ...

...mily]].<ref name="Seth 2009">{{cite book | author=Seth | title=Textbook Of Pharmacology | publisher=Elsevier India | isbn=978-8131211588 | page=III.87 | chapter=23 ...inhibitors in Alzheimer's disease | journal = British Journal of Clinical Pharmacology | volume = 48 | issue = 4 | pages = 471–80 | date = October 1999 | pmid = 1 ...

...2003 | title = Assessing non-inferiority of a new treatment in a three-arm clinical trial including a placebo | journal = [[Statistics in Medicine (journal)|St ...assay, and some applications | journal = Quarterly Journal of Pharmacy and Pharmacology | volume = 17 | pages = 117–123 }} ...

...e |first2=S. |last3=Sharma |first3=S. |last4=Asif Ansari |first4=M. |title=Clinical Updates on Drug-Induced Cardiotoxicity |journal=International Journal of Ph ...024-09-12 |title=Cardiotoxicity of Anticancer Drugs: Molecular Mechanisms, Clinical Management and Innovative Treatment |journal=Drug Design, Development and T ...

...per and Row, New York, 1968.</ref> The principle has wide applicability in pharmacology, physiology, nutrition, biochemistry, and system dynamics. It applies whene ...Churchill-Livingstone, New York, 1990</ref><ref>Okpako, D.T. Principles of Pharmacology: A Topical Approach. Cambridge University Press. 1991.</ref> If the same dr ...

...tetraenoic acid (5-oxo-ETE) on feline granulocytes | journal = Biochemical Pharmacology | volume = 96 | issue = 3 | pages = 247–55 | date = August 2015 | pmid = 26 ...ga-oxidized metabolites in the mouse macrophage | journal = The Journal of Pharmacology and Experimental Therapeutics | volume = 296 | issue = 2 | pages = 293–305 ...

...ters of Thyroid Homeostasis: Emerging Tools for Differential Diagnosis and Clinical Research |journal=Frontiers in Endocrinology |date=9 June 2016 |volume=7 |p == Clinical significance == ...

...the [[Johns Hopkins University School of Medicine]] under Chairman of the Pharmacology Department, [[Paul Talalay]], during 1970–1972. ...om the directorship of Preclinical Pharmacology Core Laboratory, Molecular Pharmacology & Chemistry Program of MSKCC, and established the PD Science LLC in 2013 in ...

...ady for decades in use for clinical application, the limited resolution of clinical SPECT (~10&nbsp;mm) stimulated the development of dedicated small animal SP ...applications are oncology, neurology, psychiatry, cardiology, orthopedics, pharmacology and internal medicine. ...

...chapter-url=https://books.google.com/books?id=-YI9P2DLe9UC&pg=PA106|title=Clinical Anesthesia|date=2009|publisher=Lippincott Williams & Wilkins|isbn=978-0-781 [[Category:Pharmacology]] ...

...ters of Thyroid Homeostasis: Emerging Tools for Differential Diagnosis and Clinical Research | journal = Frontiers in Endocrinology | volume = 7 | pages = 57 | == Clinical significance == ...