Katal

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Revision as of 17:19, 15 December 2024 by 91.165.229.20 (talk) (Undid revision 1240796460 by Christian75 (talk) (Even though 1 kat = 1 mol/s, katal is a unit of measure for *a quantity of _enzyme activity_*, not a unit of measure for a *rate of conversion*. One should not confuse the quantity that is considered with the dimensions or units that are used to express that quantity.))
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Template:Short description Template:For Template:Cleanup Template:Infobox Unit The katal (symbol: kat) is that catalytic activity that will raise the rate of conversion by one mole per second in a specified assay system.[1] It is a unit of the International System of Units (SI)[1] used for quantifying the catalytic activity of enzymes (that is, measuring the enzymatic activity level in enzyme catalysis) and other catalysts.

The unit "katal" is not attached to a specified measurement procedure or assay condition, but any given catalytic activity is: the value measured depends on experimental conditions that must be specified.[2][3] Therefore, to define the quantity of a catalyst in katals, the catalysed rate of conversion (the rate of conversion in presence of the catalyst minus the rate of spontaneous conversion) of a defined chemical reaction is measured in moles per second.[4] One katal of trypsin, for example, is that amount of trypsin which breaks one mole of peptide bonds in one second under the associated specified conditions.Template:Clarify

Definition

One katal refers to an amount of enzyme that gives a catalysed rate of conversion of one mole per second.[5][6] Because this is such a large unit for most enzymatic reactions, the nanokatal (nkat) is used in practice.[6]

kat=mols

The katal is not used to express the rate of a reaction; that is expressed in units of concentration per second, as moles per liter per second. Rather, the katal is used to express catalytic activity, which is a property of the catalyst.

SI multiples

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History

The General Conference on Weights and Measures and other international organizations recommend use of the katal.[7] It replaces the non-SI enzyme unit of catalytic activity. The enzyme unit is still more commonly used than the katal,[6] especially in biochemistry.Template:Citation needed[8] The adoption of the katal has been slow.[6][9]

Origin

The name "katal" has been used for decades. The first proposal to make it an SI unit came in 1978,[6][10] and it became an official SI unit in 1999.[6][11][12] The name comes from the Ancient Greek κατάλυσις (katalysis), meaning "dissolution";[13] the word "catalysis" itself is a Latinized form of the Greek word.[13][14]

References

Template:Reflist

  • Unit "katal" for catalytic activity (IUPAC Technical Report) Pure Appl. Chem. Vol. 73, No. 6, pp. 927–931 (2001) [1]
  • Template:Cite journal

Template:SI units