Amine oxidase

An amine oxidase is an enzyme that catalyzes the oxidative cleavage of alkylamines into aldehydes and ammonia:^[1]

RCH₂NH₂ + H₂O + O₂

⇌

RCHO + NH₃ + H₂O₂

Amine oxidases are divided into two subfamilies based on the cofactor they contain:

Class	Cofactor	Subclass	Enzyme Commission number	Human genes
Amine oxidase (formerly Template:EC number)	copper	lysyl oxidase	Template:EC number	LOX
		primary-amine oxidase	Template:EC number	AOC2, AOC3
		diamine oxidase	Template:EC number	AOC1
Monoamine oxidase	flavin	N/A	Template:EC number	MAOA, MAOB

References