Adenosylcobinamide-phosphate synthase

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Template:Short description Template:Infobox enzyme Adenosylcobinamide-phosphate synthase (Template:EnzExplorer, CbiB) is an enzyme with systematic name adenosylcobyric acid:(R)-1-aminopropan-2-yl phosphate ligase (ADP-forming).[1][2] This enzyme catalyses the following chemical reaction

(1) ATP + adenosylcobyric acid + (R)-1-aminopropan-2-yl phosphate ADP + phosphate + adenosylcobinamide phosphate
(2) ATP + adenosylcobyric acid + (R)-1-aminopropan-2-ol ADP + phosphate + adenosylcobinamide

One of the substrates, (R)-1-aminopropan-2-yl phosphate, is produced by CobD (Template:EC number). This enzyme is part of the biosynthetic pathway to cobalamin (vitamin B12) in bacteria.

See also

References

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