Alpha-bisabolene synthase

Template:Short description Template:Infobox enzyme α-Bisabolene synthase (EC 4.2.3.38, bisabolene synthase) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase ((E)-α-bisabolene-forming).

This enzyme catalyses the following chemical reaction:

(2E,6E)-farnesyl diphosphate $\rightleftharpoons$ (E)-α-bisabolene + diphosphate

This synthase requires a divalent cation cofactor (Mg²⁺ or, to a lesser extent, Mn²⁺) to neutralize the negative charge of the diphosphate leaving group.

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