Glycopeptide alpha-N-acetylgalactosaminidase
Template:Infobox enzyme Endo-α-N-acetylgalactosaminidase (Template:EC number, endo-α-acetylgalactosaminidase, endo-α-N-acetyl-D-galactosaminidase, mucinaminylserine mucinaminidase, D-galactosyl-3-(N-acetyl-α-D-galactosaminyl)-L-serine mucinaminohydrolase, endo-α-GalNAc-ase, D-galactosyl-N-acetyl-α-D-galactosamine D-galactosyl-N-acetyl-galactosaminohydrolase) is an enzyme with systematic name glycopeptide-D-galactosyl-N-acetyl-α-D-galactosamine D-galactosyl-N-acetyl-galactosaminohydrolase.[1][2][3][4][5][6][7] This enzyme catalyses the following chemical reaction
- 3-O-beta-D-galactosyl-N-acetyl-alpha-D-galactosaminyl-L-serine-[protein] + H2O 3-O-beta-D-galactosyl-N-acetyl-alpha-D-galactosamine + L-serine-[protein]
The enzyme catalyses the release of Gal-(1->3)-beta-GalNAc alpha-linked to serine or threonine residues of mucin-type glycoproteins.
Glycopeptide α-N-acetylgalactosaminidases belong to family GH101 of glycoside hydrolases.[8]
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Template:Sugar hydrolases Template:Enzymes Template:Portal bar