N1-acetylpolyamine oxidase

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Template:Infobox enzyme N1-acetylpolyamine oxidase (Template:EC number, hPAO-1, mPAO, hPAO) is an enzyme with systematic name N1-acetylpolyamine:oxygen oxidoreductase (3-acetamidopropanal-forming).[1][2][3][4] This enzyme catalyses the following chemical reaction

(1) N1-acetylspermidine + O2 + H2O ⇌ putrescine + 3-acetamidopropanal + H2O2
(2) N1-acetylspermine + O2 + H2O ⇌ spermidine + 3-acetamidopropanal + H2O2

This enzyme also catalyses the reaction:

N1,N12-diacetylspermine + O2 + H2O ⇌ N1-acetylspermidine + 3-acetamamidopropanal + H2O2.

References

Template:Reflist

Template:CH-NH oxidoreductases Template:Enzymes Template:Portal bar

  1. ↑ Template:Cite journal
  2. ↑ Template:Cite journal
  3. ↑ Template:Cite journal
  4. ↑ Template:Cite journal
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