L-2-hydroxycarboxylate dehydrogenase (NAD+)
Template:Infobox enzyme L-2-hydroxycarboxylate dehydrogenase (NAD+) (Template:EC number, (R)-sulfolactate:NAD+ oxidoreductase, L-sulfolactate dehydrogenase, (R)-sulfolactate dehydrogenase, L-2-hydroxyacid dehydrogenase (NAD+), ComC) is an enzyme with systematic name (2S)-2-hydroxycarboxylate:NAD+ oxidoreductase.[1][2][3][4] This enzyme catalyses the following chemical reaction
- (2S)-2-hydroxycarboxylate + NAD+ 2-oxocarboxylate + NADH + H+
The enzyme from the archaeon Methanocaldococcus jannaschii uses as a substrate multiple (S)-2-hydroxycarboxylates including (2R)-3-sulfolactate, (S)-malate, (S)-lactate, and (S)-2-hydroxyglutarate.
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Template:Alcohol oxidoreductases Template:Enzymes Template:Portal bar