UDP-glucuronic acid dehydrogenase

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Template:Short description Template:Infobox enzyme UDP-glucuronic acid dehydrogenase (UDP-4-keto-hexauronic acid decarboxylating) (Template:EC number, UDP-GlcUA decarboxylase, ArnADH) is an enzyme with systematic name UDP-glucuronate:NAD+ oxidoreductase (decarboxylating).[1][2][3][4][5] This enzyme catalyses the following chemical reaction

UDP-glucuronate + NAD+ ⇌ UDP-beta-L-threo-pentapyranos-4-ulose + CO2 + NADH + H+

The activity is part of a bifunctional enzyme also performing the reaction of EC 2.1.2.13 (UDP-4-amino-4-deoxy-L-arabinose formyltransferase).

References

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