Limonene-1,2-diol dehydrogenase

Template:Infobox enzyme Limonene-1,2-diol dehydrogenase (Template:EC number, NAD⁺-dependent limonene-1,2-diol dehydrogenase) is an enzyme with systematic name menth-8-ene-1,2-diol:NAD⁺ oxidoreductase. This enzyme catalyses the following chemical reaction

menth-8-ene-1,2-diol + NAD⁺ $\rightleftharpoons$ 1-hydroxymenth-8-en-2-one + NADH + H⁺ (general reaction)

(1) (1S,2S,4R)-menth-8-ene-1,2-diol + NAD⁺ $\rightleftharpoons$ (1S,4R)-1-hydroxymenth-8-en-2-one + NADH + H⁺

(2) (1R,2R,4S)-menth-8-ene-1,2-diol + NAD⁺ $\rightleftharpoons$ (1R,4S)-1-hydroxymenth-8-en-2-one + NADH + H⁺

While the enzyme from the Gram-positive bacterium Rhodococcus erythropolis DCL14 can use both (1S,2S,4R)- and (1R,2R,4S)-menth-8-ene-1,2-diol as substrate, activity is higher with (1S,2S,4R)-menth-8-ene-1,2-diol as substrate.

External links

• Template:MeshName