Attributable fraction among the exposed

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Illustration of two groups: one exposed to a risk factor, and one unexposed. Exposed group has larger risk of adverse outcome (AFe = 1/3).
Group exposed to a risk factor (left) has increased risk of an adverse outcome (black) compared to the unexposed group (right). In the exposed group, one third of the adverse outcomes can be attributed to the exposure (AFe = 1/3).

In epidemiology, attributable fraction among the exposed (AFe) is the proportion of incidents in the exposed group that are attributable to the risk factor. The term attributable risk percent among the exposed is used if the fraction is expressed as a percentage.[1] It is calculated as AFe=(IeIu)/Ie=(RR1)/RR, where Ie is the incidence in the exposed group, Iu is the incidence in the unexposed group, and RR is the relative risk.[2] It is used when an exposure increases the risk, as opposed to reducing it, in which case its symmetrical notion is preventable fraction among the unexposed.

Synonyms

Multiple synonyms of AFe are in use: attributable fraction,[1][3] relative attributable risk,[1] attributable proportion among the exposed,[1] and attributable risk among the exposed.[4]

Similarly, attributable risk percent (ARP) is used as a synonym for the attributable risk percent among the exposed.[3]

In climatology, fraction of attributable risk (FAR) is used to denote a proportion of adverse event risk attributable to the human influence on climate or other forcing factor.[5]

Numerical example

Template:RCT risk increase example

See also

References

Template:Reflist

Template:Medical research studies