Lactosylceramide 4-alpha-galactosyltransferase
Template:Short description Template:Infobox enzyme In enzymology, a lactosylceramide 4-alpha-galactosyltransferase (Template:EC number) is an enzyme that catalyzes the chemical reaction
- UDP-galactose + beta-D-galactosyl-(1->4)-D-glucosylceramide UDP + alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-D- glucosylceramide
Thus, the two substrates of this enzyme are UDP-galactose and [[beta-D-galactosyl-(1->4)-D-glucosylceramide]], whereas its 3 products are UDP, [[alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-D-]], and glucosylceramide.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-galactose:lactosylceramide 4II-alpha-D-galactosyltransferase. Other names in common use include Galbeta1-4Glcbeta1-Cer alpha1,4-galactosyltransferase, globotriaosylceramide/CD77 synthase, and histo-blood group Pk UDP-galactose. This enzyme participates in glycosphingolipid biosynthesis - globoseries and glycan structures - biosynthesis 2.
References
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