Glycine transaminase

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Template:Infobox enzyme In enzymology, a glycine transaminase (Template:EC number) is an enzyme that catalyzes the chemical reaction

glycine + 2-oxoglutarate glyoxylate + L-glutamate

Thus, the two substrates of this enzyme are glycine and 2-oxoglutarate, whereas its two products are glyoxylate and L-glutamate.

This reactions strongly favours synthesis of glycine.[1] This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is glycine:2-oxoglutarate aminotransferase. Other names in common use include glutamic-glyoxylic transaminase, glycine aminotransferase, glyoxylate-glutamic transaminase, L-glutamate:glyoxylate aminotransferase, and glyoxylate-glutamate aminotransferase. This enzyme participates in glycine, serine and threonine metabolism. It employs one cofactor, pyridoxal phosphate.

References

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  1. Textbook of Biochemistry for Medical Students, by DM Vasudevan, Sreekumari S, Kannan Vaidyanathan, 9th edition, page 283.