Glutamate N-acetyltransferase

Template:Short description Template:Inline citations needed Template:Infobox enzyme In enzymology, a glutamate N-acetyltransferase (Template:EC number) is an enzyme that catalyzes the chemical reaction

N₂-acetyl-L-ornithine + L-glutamate $\rightleftharpoons$ L-ornithine + N-acetyl-L-glutamate

Thus, the two substrates of this enzyme are N2-acetyl-L-ornithine and L-glutamate, whereas its two products are L-ornithine and N-acetyl-L-glutamate.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is N2-acetyl-L-ornithine:L-glutamate N-acetyltransferase. This enzyme participates in the urea cycle and metabolism of amino groups.

Structural studies

As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes Template:PDB link, Template:PDB link, Template:PDB link, and Template:PDB link.

References

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