N-methylhydantoinase (ATP-hydrolysing)
Template:Infobox enzyme In enzymology, an N-methylhydantoinase (ATP-hydrolysing) (Template:EC number) is an enzyme that catalyzes the chemical reaction[1]
- ATP + N-methylimidazolidine-2,4-dione + 2 H2O ADP + phosphate + N-carbamoylsarcosine
The 3 substrates of this enzyme are ATP, N-methylimidazolidine-2,4-dione, and H2O, whereas its 3 products are ADP, phosphate, and N-carbamoylsarcosine.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amides. The systematic name of this enzyme class is N-methylimidazolidine-2,4-dione amidohydrolase (ATP-hydrolysing). Other names in common use include N-methylhydantoin amidohydrolase, methylhydantoin amidase, N-methylhydantoin hydrolase, and N-methylhydantoinase. This enzyme participates in arginine, creatinine, and proline metabolism.
References
Template:Carbon-nitrogen non-peptide hydrolases Template:Enzymes Template:Portal bar
- ↑ Nucleoside triphosphate-dependent 1-methylhydantoinase, a process for obtaining it and the use - United States Patent 4816393. Inventors: Siedel Joachim, Deeg Rolf, Roder Albert, Ziegenhorn Joachim, Mollering Hans, Gauhl Helmgard. Assignee: Boehringer Mannheim. Application Date: 1985-02-25. Publication Date: 1989-03-28.