Agmatinase
Template:Short description Template:Infobox enzyme In enzymology, an agmatinase (Template:EC number) is an enzyme that catalyzes the chemical reaction
- agmatine + H2O putrescine + urea
Thus, the two substrates of this enzyme are agmatine and H2O, whereas its two products are putrescine and urea.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amidines. The systematic name of this enzyme class is agmatine amidinohydrolase. Other names in common use include agmatine ureohydrolase. This enzyme participates in urea cycle and metabolism of amino groups.
Genetics
Template:Infobox gene In humans, the enzyme is encoded by the AGMAT gene.[1][2][3][4]
Structural studies
As of late 2007, 5 structures have been solved for this class of enzymes, with PDB accession codes Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, and Template:PDB link.
Inhibitors
References
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External links
Template:Amino acid metabolism enzymes Template:Carbon-nitrogen non-peptide hydrolases Template:Enzymes Template:Portal bar