Vitamin B12-transporting ATPase

Template:Infobox enzyme In enzymology, a vitamin B₁₂-transporting ATPase (Template:EC number) is an enzyme that catalyzes the chemical reaction

ATP + H₂O + vitamin B_12out $\rightleftharpoons$ ADP + phosphate + vitamin B_12in

The 3 substrates of this enzyme are ATP, H₂O, and vitamin B₁₂, whereas its 3 products are ADP, phosphate, and vitamin B₁₂.

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides to catalyse transmembrane movement of substances. The systematic name of this enzyme class is ATP phosphohydrolase (vitamin B₁₂-importing). This enzyme participates in abc transporters - general.

Structural studies

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes Template:PDB link and Template:PDB link.

References

• Template:Cite journal
• Template:Cite journal
• Template:Cite journal

Template:3.6-enzyme-stub