NAD+ diphosphatase
Template:Short description Template:Infobox enzyme In enzymology, a NAD+ diphosphatase (Template:EC number) is an enzyme that catalyzes the chemical reaction
- NAD+ + H2O AMP + NMN
Thus, the two substrates of this enzyme are NAD+ and H2O, whereas its two products are AMP and NMN.
This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides in phosphorus-containing anhydrides. The systematic name of this enzyme class is NAD+ phosphohydrolase. Other names in common use include nicotinamide adenine dinucleotide pyrophosphatase, NADP+ pyrophosphatase, and NADH pyrophosphatase. This enzyme participates in nicotinate and nicotinamide metabolism.
Structural studies
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code Template:PDB link.
References
Template:Acid anhydride hydrolases Template:Enzymes Template:Portal bar