CDP-glucose 4,6-dehydratase

Template:Short description Template:Infobox enzyme The enzyme CDP-glucose 4,6-dehydratase (Template:EnzExplorer) catalyzes the chemical reaction

CDP-glucose $\rightleftharpoons$ CDP-4-dehydro-6-deoxy-D-glucose + H₂O

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. This enzyme participates in starch and sucrose metabolism. It employs one cofactor, NAD⁺.

Nomenclature

The systematic name of this enzyme class is CDP-glucose 4,6-hydro-lyase (CDP-4-dehydro-6-deoxy-D-glucose-forming). Other names in common use include:

• cytidine diphosphoglucose oxidoreductase, and
• CDP-glucose 4,6-hydro-lyase.

Structural studies

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes Template:PDB link and Template:PDB link.

References

• Template:Cite journal
• Template:Cite journal
• Template:Cite journal

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